The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1.Through the combination of functional adhesion assays with structural analysis using FRAP, we investigated the functional role of the other domains of CX3CL1, i.e., its mucin stalk
INTRODUCTION:Crowdsourcing, a participatory approach to solicit ideas from a large group of diverse individuals, provides an opportunity to nurture youth participation in HIV self-testing service design.The objective of this study was to describe the responses to a crowdsourcing contest aimed at soliciting ideas on how to promote HIV self-testing (
The traditional maneuver decision-making approaches are highly dependent on accurate and complete situation information, and their decision-making Freezer quality becomes poor when opponent information is occasionally missing in complex electromagnetic environments.In order to solve this problem, an autonomous maneuver decision-making approach is d
Abstract Oxyberberine (OBB) is a significant natural compound, with excellent hepatoprotective properties.However, the poor water solubility of OBB hinders its release and absorption thus resulting in low bioavailability.To overcome these drawbacks of OBB, amorphous spray-dried powders (ASDs) of OBB were formulated.The dissolution, characterization
ABSTRACT: Objective: To describe an unusual presentation of a patient with recurrent pituitary apoplexy of an adenoma that switched phenotypes from a nonfunctioning, or silent gonadotroph adenoma (SGA), to a silent corticotroph adenoma (SCA).We discuss the potential etiologies of both recurrent pituitary apoplexy and phenotype switching Nail Harden